Most strikeouts in a Major League Baseball game by a batter
- Who
- Jonathan India
- What
- 5 total number
- Where
- Not Applicable
- When
- 11 September 2022
The Major League Baseball (MLB) record for most times striking out in a 9-inning game is 5 and has been achieved nearly 200 times since 1901, most recently by Jonathan India (USA) playing for the Cincinnati Reds against the Milwaukee Brewers (both USA) on 11 September 2022.