Most strikeouts in a Major League Baseball (MLB) career by a left-handed pitcher
- Who
- Randy Johnson
- What
- 4875 total number
- When
- 2009
The record for most career strikeouts by a left handed pitcher is 4,875 by Randy Johnson (USA) playing for the Montreal Expos (Canada), Seattle Mariners (USA), Houston Astros (USA), Arizona Diamondbacks (USA), and New York Yankees (USA) from 1988 to 2009.