Most assists in a Major League Soccer game

- Who
- Lionel Messi
- What
- 5 total number
- Where
- United States (Fort Lauderdale)
- When
- 05 May 2024
The most assists in a Major League Soccer game is 5, achieved by Lionel Messi (Argentina) playing for Inter Miami against the New York Red Bulls at Chase Stadium in Fort Lauderdale, Florida, USA, on 5 May 2024.
Messi scored a goal and set up two for Matías Rojas and a hat-trick for Luis Suárez – all in the second half of the game against New York. Miami won the match 6–2, having trailed 1–0 at the break. Although the MLS counts up to two assists per goal, all five of Messi’s were “primary”, i.e., the final pass to the goal scorer.