Most yards gained rushing in an NFL game

Most yards gained rushing in an NFL game
Who
Adrian Peterson
What
296 yard(s)
When
04 November 2007

The record for most yards gained rushing in an NFL game is 296 yds (270.6 m) gained by Adrian Peterson (USA) of the Minnesota Vikings in a game against the San Diego Chargers at the Metrodome in Minneapolis, Minnesota, USA, on 4 November 2007.

The Minnesota Vikings won 35-17.