Most World Motorcycle Championship career race starts in MotoGP/500 cc
- Who
- Valentino Rossi
- What
- 372 total number
- Where
- Spain
- When
- 14 November 2021
The most race starts in MotoGP/500 cc is 372, achieved by Valentino Rossi (Italy) between 19 March 2000 and 14 November 2021.
The seven-time MotoGP world champion won 89 of his 372 starts, and stood on the podium 199 times. He also recorded 30 starts in both the 125cc and 250cc championships, for a total motorcycle Grand Prix career tally of 432.