Most home runs in a postseason Major League Baseball (MLB) game
- Who
- Shohei Ohtani, Chris Taylor, Enrique Hernandez, Jose Altuve, Pablo Sandoval, Albert Pujols, Adrian Beltre, Adam Kennedy, George Brett, Reggie Jackson, Bob Robertson, Babe Ruth
- What
- 3 total number
- Where
- Not Applicable
- When
- 17 October 2025
The Major League Baseball record for most home runs hit by an individual in a postseason game is three and has been accomplished by 12 players. The most recent person to achieve this was Shohei Ohtani (Japan) of the Los Angeles Dodgers in Game Four of the 2025 National League Championship Series on 17 October 2025. Previously, the feat had been achieved by: Chris Taylor (USA) of the Los Angeles Dodgers in Game 5 of the National League Championship Series on 21 October 2021; Enrique Hernandez (Puerto Rico) of the Los Angeles Dodgers in Game 5 of the National League Championship Series on 19 October 2017; Jose Altuve (Venezuela) of the Houston Astros in Game 1 of the American League Division Series on 5 October 2017; Pablo Sandoval (Venezuela) of the San Francisco Giants in Game 1 of the 2012 World Series; Albert Pujols (Dominican Republic) of the St. Louis Cardinals in Game 3 of the 2011 World Series; Adrian Beltre (Dominican Republic) of the Texas Rangers in Game 4 of the 2011 ALDS; Adam Kennedy (USA) of the Los Angeles Angels in Game 5 of the 2002 AL Championship Series; George Brett (USA) of the Kansas City Royals in Game 3 of the 1978 ALCS; Reggie Jackson (USA) of the New York Yankees in Game 6 of the 1977 World Series; Bob Robertson (USA) of the Pittsburgh Pirates in Game 2 of the 1971 NLCS; and Babe Ruth (USA) of the New York Yankees in Game 4 of the 1926 World Series and Game 4 of the 1928 World Series.
Ohtani was also the starting pitcher in this historic game. He pitched six shutout innings and struck out 10 batters.