Most strikeouts in an extra-inning Major League Baseball (MLB) game (both teams)
- Who
- New York Yankees, Chicago Cubs, Arizona Diamondbacks, St. Louis Cardinals
- What
- 48 total number
- Where
- Not Applicable
- When
- 24 September 2019
The MLB record for most combined strikeouts by both teams in a game is 48, and has been accomplished twice. First by the pitching staffs of the New York Yankees (26) and Chicago Cubs (22) in a game that lasted 18 innings at Chicago’s Wrigley Field on 7 May 2017, and then by the pitching staffs of the Arizona Diamondbacks (25) and St. Louis Cardinals (23) in a 19-inning game at Arizona’s Chase Field on 24 September 2019.