Most games gaining 200 yards rushing in an NFL career

Most games gaining 200 yards rushing in an NFL career
Who
Derrick Henry, Adrian Peterson, O.J. Simpson
What
6 total number
Where
Not Applicable
When
30 October 2022

When Derrick Henry of the Tennessee Titans rushed for 219 yards against the Houston Texans on 30 October 2022, it was the sixth game in his career surpassing 200 yards rushing, tying the record first set by O.J. Simpson and then equalled by Adrian Peterson (all USA).

Henry’s 200-yard rushing game against Houston was his fourth against the Texans, setting a record for the most such games against a single team in NFL history.