Smallest logo, single DNA strand

Smallest logo, single DNA strand
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Who
Michael Hudoba
What
103x55 nanometre(s)
Where
United States (Urbana-Champaign)
When
05 August 2014

The smallest logo constructed from a single uninterrupted DNA strand is the 103-by-55-nanometers "O H I O" (Ohio State University) logo, with the actual traced writing measuring 441.882 nm in length. The logo was designed by Michael Hudoba and presented to the public on 5 August 2014 at the 3rd Midwest Single Molecule Workshop at the University of Illinois in Urbana-Champaign, Illinois, USA.

This example of DNA “origami” writing is made using a modified version of the genome of the M13mp18 bacteriophage, which is 8,064 bases long. To form the logo of the Ohio State University, USA, these bases were arranged into six helices connected in parallel to form a six-helix bundle. In the six-helix bundle, each helix is 1,323 DNA base-pairs long (where the length of a base-pair is 0.334 nm). Other scientists have made text using DNA origami, but they used many different DNA pieces and not just one long strand, resulting in individual letters that are much larger than the Ohio State University DNA origami logo.