- Lionel Messi
- 36 total number
- Spain ()
The most hat-tricks in a La Liga career is 36, achieved by Lionel Messi (Argentina) playing for FC Barcelona from 10 March 2007 to 22 February 2020.
Lionel Messi surpassed Cristiano Ronaldo's tally of 34 with three goals in Barcelona’s 5-2 win over RCD Mallorca on 7 December 2019.